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Role of Stx during macrophages infection. (A) Bacterial uptake (percent compared to inoculum) and survival (percent compared to 0 h) of the stx mutants. (B) Cytotoxicity of strain EDL933 O157:H7 and isogenic mutants measured by LDH release after 24 h of infection. The figures show the means ± standard deviations from at least three independent experiments. An asterisk indicates a significant difference compared to EDL933 (P < 0.05).
