TABLE 2.

Lung inflammation in naïve and BCG-vaccinated mice at 4 and 20 weeks postchallenge with nine different M. tuberculosis strains

Infection strain	Mean inflammation value (% of lung section inflamed) for the group at:a
	4 wk postchallenge		20 wk postchallenge
	Naïve mice	BCG-vaccinated mice	Naïve mice	BCG-vaccinated mice
Erdman	48.8 ± 3.0	13.1 ± 2.1**	38.7 ± 1.5	25.5 ± 1.1**
C913	36.4 ± 4.2	24.8 ± 2.4*	34.0 ± 0.8	18.0 ± 1.7**
CDC1551	72.3 ± 2.5	35.9 ± 1.8**	37.8 ± 1.7	23.6 ± 2.5**
ChS	34.4 ± 2.5	11.7 + 4.3**	53.9 ± 7.7	24.4 ± 1.3**
HN878	49.3 ± 4.0	16.5 ± 1.4**	43.6 ± 5.2	23.2 ± 2.7*
N4	39.6 ± 3.4	15.4 ± 3.8*	47.3 ± 9.0	15.2 ± 2.5*
NHN5	35.3 ± 3.7	24.7 ± 2.8*	42.7 ± 2.9	16.8 ± 1.4**
NY669	47.5 ± 7.0	16.0 ± 0.6**	56.1 ± 0.2b	29.9 ± 3.5*
NY920	38.9 ± 5.8	19.4 ± 1.2**	36.3 ± 6.2	20.1 ± 4.4*

^aMean percentage of the area of inflammation ± standard error of the mean. Significantly reduced lung inflammation in the BCG-vaccinated mice relative to naïve controls is indicated as follows: *, P < 0.05; **, P < 0.01.

^bSince naïve mice infected with NY669 died prior to the 20-week time point, these mice were sacrificed at 16 weeks postchallenge.