TABLE 3.
Colon crypt length in C57BL/6 mice infected with derivatives of C. rodentium ICC169
| Strain of C. rodentiuma | Crypt length (μm) onb:
|
||
|---|---|---|---|
| Day 6 | Day 10 | Day 14 | |
| None | 141 ± 12 | 136 ± 18 | 124 ± 18 |
| P1A2 | 151 ± 25 | 160 ± 11 | 145 ± 16 |
| EMH1 | 189 ± 21 | 214 ± 18 | 190 ± 19 |
| ICC169 | 208 ± 18c,d | 221 ± 27c | 292 ± 27c,d |
a
C57BL/6 mice were orally inoculated with approximately 2 × 109 CFU C. rodentium wild-type strain ICC169 or regA mutant P1A2 or EMH1.
b
The values are the means ± standard errors of the means for three to five individual animals.
c
The value is significantly higher than the value for mice infected with strain P1A2 at the same time (P < 0.05, two-tailed Student's t test).
d
The value is significantly higher than the value for mice infected with strain EMH1 at the same time (P < 0.05, two-tailed Student's t test).