Table 2.
Genetic model parameter values used to generate the simulated data
Genetic parameter value |
|||||||
---|---|---|---|---|---|---|---|
Group | Models | q | f2 | f1 | f0 | θ** | a* |
No | D100 | 0.01 | 1 | 1 | 0 | 0.1 | 0.5 |
Phenocopy | R100 | 0.01 | 1 | 0 | 0 | 0.1 | 0.5 |
Models | D80 | 0.01 | 0.8 | 0.8 | 0 | 0.1 | 0.5 |
R80 | 0.01 | 0.8 | 0 | 0 | 0.1 | 0.5 | |
D100-Q10 | 0.1 | 1 | 1 | 0 | 0.1 | 0.5 | |
A50 | 0.01 | 1 | 0.5 | 0 | 0.1 | NA | |
Phenocopy | D100-P10 | 0.01 | 1 | 1 | 0.1 | 0.01 | NA |
Models | D90-P05 | 0.01 | 0.9 | 0.9 | 0.05 | 0.01 | NA |
I80-P05 | 0.01 | 1 | 0.8 | 0.05 | 0.01 | NA |
a denotes the proportion of unlinked families to the marker assuming heterogeneity.
For double ascertainment models, θ = 0.1 for every model.