Table 6. P values for haplotype rs1048661/rs3825942 in comparisons between cases (EX, EG, and EX+EG) and controls (CT, NG, PG+NG, CT+NG, and CT+PG+NG).
| |
EX | ||||
|---|---|---|---|---|---|
|
Versus
CT |
Versus NG |
Versus
PG+NG |
Versus
CT+NG |
Versus
CT+PG+NG |
|
| TG |
9.56x10-21 |
NA |
9.56x10-21 |
6.19x10-17 |
1.27x10-21 |
| GG |
9.69x10-11 |
NA |
9.69x10-11 |
1.76x10-10 |
1.43x10-10 |
| GA |
1.01x10-6 |
NA |
1.01x10-6 |
5.63x10-7 |
5.63x10-7 |
| |
EG |
||||
|
Versus
CT |
Versus
NG |
Versus
PG+NG |
Versus
CT+NG |
Versus
CT+PG+NG |
|
| TG |
1.83x10-28 |
4.95x10-21 |
3.06x10-23 |
9.77x10-30 |
4.40x10-20 |
| GG |
3.12x10-15 |
2.51x10-11 |
4.82x10-12 |
2.60x10-15 |
3.70x10-15 |
| GA |
5.63x10-9 |
8.10x10-9 |
4.08x10-9 |
3.02x10-9 |
2.36x10-9 |
| |
EX+EG |
||||
|
Versus
CT |
Versus
NG |
Versus
PG+NG |
Versus
CT+NG |
Versus
CT+PG+NG |
|
| TG |
1.23x10-40 |
7.84x10-29 |
1.24x10-32 |
5.89x10-43 |
8.27x10-44 |
| GG |
5.93x10-22 |
4.01x10-15 |
1.03x10-16 |
2.39x10-22 |
2.83x10-22 |
| GA | 1.17x10-13 | 3.98x10-13 | 9.33x10-14 | 3.68x10-14 | 2.25x10-14 |
Significant association was found between cases and controls. EX, exfoliation syndrome; EG, exfoliation glaucoma; PG, primary open angle glaucoma aged 70 years or older; NG, normal tension glaucoma aged 70 years or older; and CT, cataract aged 70 years or older. NA, not available due to a small number of samples.