Table 2.

Comparison of Selected Members of the ERV/ALR Family

Protein a	# electrons to dihydroflavinb	Maximum # of electronsc	Flavin/Thiolate CT complexd	Blue Semiquinoned	TN/min with 5 mM DTT	TN/min with RNasered (200 µM –SH)
Erv2pe	4	6	No	Yes	63	6 (200 uM SH)
ALR short formf	2	4	No	Yes	46	~0
QSOX-Erv domaing	2	6	No	Yes	20	~0
QSOX completeh	4	8	Yes	No	1005	630

^aProteins sources: Erv2p from S. cerevisiae, human ALR short form, QSOX Erv domain and complete protein were from avian egg white.

^bDenotes the number of electrons delivered during dithionite titrations when full reduction of the flavin is observed.

^cElectron equivalents derived from multiplying the total number of known redox centers by 2-electrons.

^dThiolate to oxidized flavin charge-transfer complex or blue semiquinone observed during anaerobic reductive titrations of the proteins.

^eThis work.

^fFarrell and Thorpe (25).

^gRaje and Thorpe (29).

^hHoober et al. (26); Raje and Thorpe (29)