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. 2008 Oct 28;6(10):e256. doi: 10.1371/journal.pbio.0060256

Figure 5. Diverse Outcomes of REST Function on ESC and NSC Gene Expression Profiles.

Figure 5

(A and B) The numbers of genes decreasing (“down”) and increasing (“up”) in response to DN:REST treatment are shown (p < 0.01 threshold for statistical significance) for (A) NSC and (B) ESC.

(C and D) Genes with significant (p < 0.01) changes (≥3-fold) in expression were tabulated for (C) NSC and (D) ESC in response to DN:REST. Gray shaded genes are those with associated REST binding sites at the indicated distance (“Dist.”) from the TSS. Unshaded genes have no REST binding sites within 100 kbp. Common genes are printed in blue.