Figure 3. Influence of TOLLIP and TRL4 and their interaction on log PT-IgG titers.
Influence of TOLLIP (rs4963060) and TLR4 (rs6478317) interaction on log PT-IgG titers following pertussis vaccination in a dominant model of inheritance. The presence of one or two minor alleles of one of these SNPs, but not the presence of one or two minor alleles of both SNPs, was associated with a lower PT-IgG titer. 0, 1, and 2 represent the number of minor alleles. * Significantly different from the group homozygous for the wild-type alleles (p = 0.04). P interaction term = 0.01. Vertical bars indicate standard errors.
