Fig. 1.
The orexigenic effect of NPY is decreased by estradiol treatment in OVX rats. Oil- and estradiol-treated rats received intracerebroventricular infusions of 5 µg NPY or saline vehicle during the mid-light phase. Analysis of food intake during the following 24 h interval revealed that the orexigenic effect of NPY was limited to the first 2 h following drug treatment. During this interval, the orexigenic effect of NPY was greater in oil-treated rats, relative to estradiol-treated rats. *Greater than saline-treated rats, P < 0.05. +Oil/NPY group greater than estradiol/NPY group, P < 0.05.