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. 2008 Oct 31;3(10):e3615. doi: 10.1371/journal.pone.0003615

Table 3. The genes included in the current study.

Inflammation & thrombosis Gene symbol Location # variants studied in both FR92 and FR97
carboxypeptidase B2 (plasma) CPB2 13q14.12 10 yes
CD14 molecule CD14 5q31.3 3 yes
coagulation factor II (thrombin) F2 11p11.2 3
coagulation factor II (thrombin) receptor F2R 5q13.3 3
coagulation factor V (proaccelerin, labile factor) F5 1q24.2 21 yes
coagulation factor VII (serum prothrombin conversion accelerator) F7 13q34 3
coagulation factor X F10 13q34 3
coagulation factor XII F12 5q35.3 3 yes
coagulation factor XIII, A1 polypeptide F13A1 6p25.1 9 yes
C-reactive protein, pentraxin-related CRP 1q23.2 6 yes
fibrinogen alpha chain FGA 4q32.1 5 yes
fibrinogen beta chain FGB 4q32.1 5 yes
fibrinogen gamma chain FGG 4q32.1 4 yes
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) ITGA2 5q11.2 6
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 17q21.32 3
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor ICAM1 19p13.2 6 yes
interleukin 1, alpha IL1A 2q13 2
interleukin 1, beta IL1B 2q13 4
interleukin 10 IL10 1q32.1 4
interleukin 6 (interferon, beta 2) IL6 7p15.3 6
lectin, mannose-binding, 1 LMAN1 18q21.32 6
lymphotoxin alpha (TNF superfamily, member 1) LTA 6p21.33 4 yes
plasminogen activator, tissue PLAT 8p11.21 4
protein C (inactivator of coagulation factors Va and VIIIa) PROC 2q14.3 6 yes
selectin E (endothelial adhesion molecule 1) SELE 1q24.2 3
selectin L (lymphocyte adhesion molecule 1) SELL 1q24.2 6
selectin P (granule membrane protein 140kDa, antigen CD62) SELP 1q24.2 1
selenoprotein S SEPS1 15q26.3 6 yes
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 SERPINE1 7q22.1 6 yes
thrombomodulin THBD 20p11.21 9 yes
tumor necrosis factor (TNF superfamily, member 2) TNF 6p21.33 2 yes
vascular cell adhesion molecule 1 VCAM1 1p21.2 4
Lipids & energy
apoliprotein A-V APOA5 11q23.3 6 yes
apoliprotein E APOE 19q13.32 7 yes
forkhead box C2 (MFH-1, mesenchyme forkhead 1) FOXC2 16q24.1 4
lactase LCT 2q21.3 5 yes
lipin 1 LPIN1 2p25.1 7 yes
neuropeptide Y NPY 7p15.3 4 yes
thioredoxin interacting protein TXNIP 1q21.1 3
upstream stimulatory factor 1 USF1 1q23.3 6 yes
Others
5,10-methylenetetrahydrofolate reductase (NADPH) MTHFR 1p36.22 3
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ACE 17q23.3 4 yes
angiotensin II receptor, type 1 AGTR1 3q24 7 yes
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 APOBEC2 6p21.1 6 yes
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) FUT3 19p13.3 3 yes
klotho KL 13q13.1 9 yes