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. Author manuscript; available in PMC: 2009 Sep 12.
Published in final edited form as: Neurosci Lett. 2008 Jul 3;442(2):161–164. doi: 10.1016/j.neulet.2008.06.074

Fig. 2.

Fig. 2

Changes of weight bearing ratios (% weight bearing force on injured ankle/total body weight) and foot volume following an ankle ligament injury and the effect of analgesic compounds on weight bearing ratios. (A, B) ATF+CF+PTF group showed the most severely reduced weight bearing ratios and increased foot volume among 4 groups. ATF group: only ATF was cut, ATF+CF group: ATF and CF were cut, leaving the PTF intact, ATF+PTF group: ATF and PTF were cut, leaving the CF intact, and ATF+CF+PTF group: all three ligaments were cut. *P<0.05 compared with ATF group. (C) Effect of systemic morphine on the weight bearing ratios in ATF+CF+PTF injured rats. Morphine (both 2 and 5 mg/kg) significantly improved the reduced weight bearing ratios for at least 1 hr in a dose-dependent manner. *P<0.05 compared to the vehicle group. (D) Effect of systemic indomethacin on the weight bearing ratios in ATF+CF+PTF injured rats. Indomethacin (5mg/kg, i.p.)-treated rats showed significant increases of weight bearing ratios up to 6 hr, compared to vehicle control. * P<0.05 compared to the vehicle group. The data are means ± SEM.