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. 2008 Nov 5;3(11):e3646. doi: 10.1371/journal.pone.0003646

Figure 1. The bristle lineage.

Figure 1

(A) pI cells divide giving rise to two secondary precursor cells, pIIb and pIIa. The former, after two rounds of divisions, produces the inner cells and the latter, after one round of division, the outer cells. The corresponding cell cycle phases are shown in colour (modified from [19]). (B) Asymmetric cell division of pI. The differential segregation of Numb and Neuralized (Neu) during pI division triggers unidirectional Notch-signalling to the posterior cell. As such, the anterior sister cell becomes the ligand sender (N-off, pIIb) and the posterior cell the signal receiver (N-on, pIIa).