Table 2.

Mean Anti-rFVIII Inhibitory Titers after the End of 6 Weeks Following Immunization of Hemophilic Mice with rFVIII in the Absence and Presence of PS-Containing Liposomes of Varying Size

Liposome Size (nm)	Inhibitory Titers (BU/mL, Mean±SEM)	Reduction in Inhibitory Titers (Relative to Control) (%)
Control (rFVIII)	690±78 (n=13)	—
80	258*±35 (n=12)	∼63
200	215*±71 (n=14)	∼69
400	161*±27 (n=12)	∼77

^*p<0.05, statistical analysis was carried out as described under Materials and Methods Section.