Table 1.
Feature | Phase Contrast MRI (PCMRI) |
MR Tagging | Pulse Field Gradient (PFG) Methods: HARP, DENSE |
---|---|---|---|
Time Resolution | - Velocity-encoding pulses require 4ms in current scanners. - Phase difference calculation required (at least two acquisitions). - Time integration required for desplacement estimate. |
- Simple tagging pulses take ∼3 ms in each direction. - Time resolution set by imaging method. - Tag pattern detection is very insensitive to motion. |
- HARP: Multiphase acquisition is possible, time resolution is set by imaging method. - DENSE: Currently implemented only for a single phase. |
Spatial Resolution | - Resolution is determined by the dimensiion of the derivative operator (two pixel) minimum and the SNR of the velocity induced phase shift. |
- Limited by the density of tagging pattern. |
- Limited by the spatial resolution of imagging method. - In general, higher spatial resolution with DENSE. |
Acqusition Time | - Four acquisitions required for 3D deformations. |
- Depends on method used: 1-3 acquisitions required for 3D deformation. |
- Depends on method used: 1-3 acquisitions required for 3D deformation. |
MRI Physics | - Phase shifts from other processes can interfere with velocity encoding. - Steady state must be maintained during acquisition. - Motion estimated can be obtained over the entire heart cycle. |
- Tag fading from T1 recovery limits duration of motion tracking. - Tagging pattern detection is very robust to image artifacts. - Any imaging method can be used. |
- T1 recovery limits the duration of motion tracking. - Dispersive effects of intravoxel dephasing are the main limitation. |
Quantification and Visualization |
- No segmentation required for quantitative estimates. - Strain cannot be viewed directly from the raw images. - Strain-rate computed directly from spatial gradients of velocity. |
- 2D myocardial strain can be observed directly from the deformation patterns on the images. |
- Allows direct quantification of displacement. - Segmentation not necessary. - Synthetic tags can be used. |