Table 3.

Influences of losartan or nicardipine treatment in hyperthyroid rats with sympathetic denervation

Treatment	Vehicle	Losartan	Nicardipine
Serum free T3, ng/l	6.7 ± 0.8	6,7 ± 6.1	6.8 ±0.2
HW/BW, mg/g	4.7 ±0.5	3.3 ± 0.2*	4.4 ±0.2
Systolic blood pressure, mmHg	135 ±6	117 ±1*	115 ±4*
Heart rate, beats/min	447 ±5	438 ± 42	449 ±9
PRA, μg · h−1 · l−1	14 ±3	30 ±1*	12 ± 2
Cardiac renin, ng · h−1 · g−1	16 ± 2	15 ± 1	16 ± 1
Renin/GAPDH, %ratio	33 ± 4	33 ± 3	31 ± 5
Plasma ANG II, ng/l	68 ± 9	193 ± 13*	72 ± 4
Cardiac ANG II, pg/g	186 ± 9	144 ± 8*	184 ± 11

Values are means ± SE; n = 5 experiments. Definitions are as in Table 1.

^*P < 0.05 vs. vehicle treatment.