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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Surgery. 2008 Aug 10;144(4):525–532. doi: 10.1016/j.surg.2008.06.005

Table 5.

Key Clinical Trials and Case Series Evaluating Number of Sentinel Lymph Nodes Removed

Institution Total Patients SLN Positive Patients (%) Mean # SLN Removed More than 3 SLN removed (%) Number SLN Required to Identify 1st Positive SLN (%)

University of Louisville (10 3882 1358 (35.0%) Median 2 300 (22.1%)* 1- 1011 (74.4%)
2- 151 (11.1%)
3- 56 (4.1%)
>3- 35 (2.6%)

Memorial Sloan Kettering (11 1561 449 (28.8%) 2.3 241 (15.4%) 1- 338 (75.3%)
2- 79 (17.6%)
3- 23 (5.1%)
>3- 8 (1.8%)

William Beaumont (12) 720 167 (23.2%) 4.4 77 (46.1%)* 1- 128 (76.6%)
2- 24 (14.4%)
3- 10 (6.0%)
>3- 5 (3.0%)

University of Michigan (13 725 132 (18.0%) 2.5 133 (18.3%) 1- 87 (65.9%)
2- 27 (20.5%)
3- 16 (12.1%)
>3- 2 (1.5%)

Virginia Mason (14 541 129 (23.8%) 1.95 57 (10.5%) 1- 127 (98.4%)
2- NR
3- 2 (1.6%)
>3- NR

University of South Florida (15) 465 128 (27.5%) Median 2 56 (11.0%) 1- 114 (89.1%)
2- 12 (9.4%)
3- 2 (1.6%)
>3- 0 (0%)

Ludwig Boltzman (16) 263 105 (39.9%) 1.8 19 (7.2%) 1- 96 (91.4%)
2- 8 (7.6%)
3- 1 (1.0%)
>3- 0 (0%)

Ohio State University (17 353 104 (29.5%) 2.5 66 (18.7%) 1- 86 (82.7%)
2- 15 (14.4%)
3- 1 (1.0%)
>3- 1 (1.0%)

Mayo Clinic (18 472 103 (22%) 2.5 85 (18.0%) 1- 90 (87.4%)
2- 8 (7.8%)
3- 3 (2.9%)
>3- 2 (1.9%)

Wagga Wagga (19 113 33 (29.2%) 1.9 NR 1- 29 (87.9%)
2- 3 (9.1%)
3- 1 (3.0%)
>3- 1 (3.0%)

Case Western Reserve 126 38 (30.2%) 2.8 33 (26.2%) 1- 31 (81.6%)
2- 6 (15.8%)
3- 1 (2.6%)
>3- 0 (0%)
*

Represents only sentinel lymph node positive patients