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. Author manuscript; available in PMC: 2008 Oct 28.
Published in final edited form as: Bioconjug Chem. 2008 Aug 27;19(10):1987–1994. doi: 10.1021/bc800144a

Table 1.

Effect of Pluronic P123 on particle size for different polyplex compositions and component mixing orders

Polyplexa Effective Diameter (nm)b Polydispersity
DNA + P123 N/A N/A
DNA + PB25080 85 ± 3 0.096
DNA+P123+PB25080 76 ± 6 0.229
DNA+PB25080+P123 72 ± 5 0.213
DNA+P85PEI 150 ± 2 0.155
DNA+P123+P85PEI 120 ± 2 0.212
DNA+Exgen 500 180 ± 4 0.164
DNA+P123+Exgen 500 160 ± 6 0.241
a

Polyplexes were formed at N/P = 8 for PB25080 and P85PEI and N/P = 9 for Exgen 500.

b

Data are mean ± SEM (n = 5).