. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: Mol Pharmacol. 2008 Jun 3;74(3):744–754. doi: 10.1124/mol.108.045500

Table 2.

Enzyme kinetic parameter estimates obtained for hyodeoxycholic acid glucuronidation by human UGT2A3 variants (UGT2A3.1 and UGT2A3.2) expressed in SF21 insect cells.

	UGT2A3.1		UGT2A3.2
	Estimate	SE	Estimate	SE
Vmax (pmoles/min/mg)	27	2	20	2
K_m (µM)	69	7	44	12
Vmax / K_m (mL/ min /gm)	0.40	0.04	0.46	0.13