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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Mol Pharmacol. 2008 Jul 29;74(5):1345–1358. doi: 10.1124/mol.108.049551

Figure 10. VU0155041 reversed reserpine-induced akinesia in rats.

Figure 10

Rats were treated with 5 mg/kg reserpine as described in Materials and Methods. 2 hours later, animals were infused with the indicated doses of either L-AP4 or VU0155041 and a reversal of akinesia, monitored via locomotor activity, was measured. Data are plotted as baseline locomotor activity (white bars) and then the activity measured 15 minutes after compound infusion (black bars). Experiments represent data obtained for 7 rats per group. *p<0.05, Dunnett's comparison with vehicle group.