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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Bioorg Chem. 2008 May 27;36(4):190–197. doi: 10.1016/j.bioorg.2008.04.001

Figure 1.

Figure 1

Inhibitory and activating properties of arylstibonic acids on supercoil relaxation by hTopo I (black bars) and vTopo (open bars). Screening reactions contained 5 μM compound, 14 nM pUC19 plasmid DNA and 1 nM hTopo or vTopo (see Methods).