Table 3.
Pharmacodynamic parameter estimates for NTX in MM patients using a cellular bone homeostasis model.
| Parameter (units) | Final Estimate | CV% |
|---|---|---|
| DA(day−1) | 29.8 | 1.48 |
| Eb(nM) | 5.55 | 6.73 |
| EC50(pM) | 1.88 × 10−5 | 40.3 |
| n (dimensionless) | 0.745 | 25.6 |
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