Table 1.
AMPH (mg/kg) |
8-OH-DPAT (mg/kg) |
|||||||
---|---|---|---|---|---|---|---|---|
Vehicle | 0.3 | 0.6 | 1.0 | Vehicle | 0.3 | 0.6 | 1.0 | |
LCR | ||||||||
Nosepoke | 1.82 (0.25) | 1.34 (0.14)*** | 1.72 (0.19) | 1.77 (0.18) | 1.55 (0.17) | 1.87 (0.18) | 2.42 (0.53)** | 2.77 (0.48)*** |
Lever press | 2.82 (0.26) | 2.11 (0.23)** | 2.71 (0.27) | 2.68 (0.28) | 2.50 (0.25) | 2.92 (0.49) | 3.90 (0.73) | 4.64 (0.89) |
HCR | ||||||||
Nosepoke | 1.57 (0.14) | 1.30 (0.10) | 1.38 (0.10) | 1.41 (0.11) | 1.55 (0.10) | 1.81 (0.12) | 2.20 (0.19) | 2.26 (0.24) |
Lever press | 2.33 (0.33) | 2.07 (0.26) | 2.29 (0.31) | 2.28 (0.35) | 2.47 (0.25) | 3.34 (0.33) | 5.25 (0.87)** | 4.28 (0.82) |
p<0.01
p<0.001, compared to vehicle