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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2008 Jun 9;98(1-2):54–62. doi: 10.1016/j.drugalcdep.2008.04.009

Table 1.

Mean latencies (s) to nosepoke for the initiation of a trial and to choose a lever, following injection of vehicle, AMPH or 8-OH-DPAT. SEM is given in parentheses.

AMPH (mg/kg)
8-OH-DPAT (mg/kg)
Vehicle 0.3 0.6 1.0 Vehicle 0.3 0.6 1.0
LCR
Nosepoke 1.82 (0.25) 1.34 (0.14)*** 1.72 (0.19) 1.77 (0.18) 1.55 (0.17) 1.87 (0.18) 2.42 (0.53)** 2.77 (0.48)***
Lever press 2.82 (0.26) 2.11 (0.23)** 2.71 (0.27) 2.68 (0.28) 2.50 (0.25) 2.92 (0.49) 3.90 (0.73) 4.64 (0.89)
HCR
Nosepoke 1.57 (0.14) 1.30 (0.10) 1.38 (0.10) 1.41 (0.11) 1.55 (0.10) 1.81 (0.12) 2.20 (0.19) 2.26 (0.24)
Lever press 2.33 (0.33) 2.07 (0.26) 2.29 (0.31) 2.28 (0.35) 2.47 (0.25) 3.34 (0.33) 5.25 (0.87)** 4.28 (0.82)
**

p<0.01

***

p<0.001, compared to vehicle