Table 3.
E-isomer | Ki ratio PKCα/RasGRP-3 | Z-isomer | Ki ratio PKCα/RasGRP-3 |
---|---|---|---|
12a-E | 43 | — | |
12b-E | 13 | 12b-Z | 20 |
12c-E | 19 | 12c-Z | 14 |
12d-E | 14 | 12d-Z | 8 |
12e-E | 6 | 12e-Z | 3 |
12f-E | 47 | — | — |
12g-E | 32 | 12g-Z | 11 |
12h-E | 10 | 12h-Z | 4 |
12i-E | 27 | 12i-Z | 7 |
12j-E | 16 | 12j-Z | 2 |
12k-E | 8 | 12k-Z | 6 |
12l-E | 64 | — | — |
12m-E | 119 | 12m-Z | 16 |
12n-E | 47 | 12n-Z | 5 |
12o-E | 45 | 12o-Z | 20 |
12p-E | 31 | 12p-Z | 17 |
12q-E | 27 | 12q-Z | 5 |
12r-E | 165 | — | — |