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Histopathological appearance of intact (A) and degraded (B) RSH from a rat treated with 1% HD for 18d. Intact RSH appear similar to step 19 spermatids with smooth curved edges and dense hematoxylin staining. Degraded RSH appear thinner with jagged edges, are sometimes bent at more acute angles, and stain less intensely with hematoxylin, often appearing PAS positive. PASH stained 3μm plastic sections; bars = 10μm.
