Effects of adolescent fluoxetine treatment on adult fear conditioning and extinction in BALB/cJ and C57BL/6J mice. There were no differences in freezing during conditioning, extinction, or extinction recall between BALB/cJ mice receiving the lower dose (a, left panel) or higher dose (b, left panel) of fluoxetine (FLX) relative to water-treated controls. C57BL/6J mice treated with the lower dose (a, right panel) but not higher dose (b, right panel) of fluoxetine showed normal freezing during conditioning but decreased freezing during fear recall, compared to water-treated controls, while rates of extinction were not affected by fluoxetine treatment. n=8–10/strain/treatment. *p<0.05 same trial block in water-treated C57BL/6J mice. Data are means±SEM