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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Chem Res Toxicol. 2008 May 22;21(6):1295–1303. doi: 10.1021/tx800059j

Figure 4.

Figure 4

Representative plots of absorbance changes elicited by increasing concentrations of (+)-, (-)- or (±)-PCB 136 with rat hepatic microsomes (3 separate experiments for PB, DEX and CO, single experiment for MC). Increasing amounts of PCB were added separately to 1 mL sample cuvettes containing hepatic microsomes at 4 nmol P450/mL prepared from MC- (A), PB- (B), DEX- (C), and CO-treated (D) rats. Difference spectra were recorded and ΔA values calculated as described in Experimental Procedures.