. Author manuscript; available in PMC: 2009 Aug 1.

Published in final edited form as: Clin Exp Pharmacol Physiol. 2008 Apr 21;35(8):957–964. doi: 10.1111/j.1440-1681.2008.04934.x

Table 4.

Changes in Oxygen-Sensitive Genes in Wound-Edge of Patients Treated with HBO

		Count	Expression, mean
Gene	Oxygen Treatment	Healing : Not Healing	Wounds Not Healing	Wounds Healing	Wounds Healing to not healing Ratio	p- value¹
VEGF	HBO	14 : 3	1.12	1.38	1.23	0.995
TGFβ1	HBO	14 : 3	1.67	2.29	1.37	0.190
COL1A1	HBO	14 : 3	0.87	2.49	2.86	0.415

Results from T₀ versus T₁ shown.

p-value is testing if the healing to not-healing wound volume is significantly greater than 1.0 as determined from linear regression of natural log transformed gene expression values from healing (yes/no) and is adjusted for the patient’s age