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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Nat Genet. 2008 Jun 29;40(8):955–962. doi: 10.1038/NG.175

Figure 2.

Figure 2

A quantile-quantile plot of observed -log10 p values versus the expectation under the null. Black points represent the complete meta-analysis, with a substantial departure from the null at the tail (values > 8 are represented along the top of the plot as triangles). Dark blue points show the distribution after removing 11 previously published loci, demonstrating a still notable excess. Light blue points show the distribution after removing all 40 loci which replicate at least nominally. In all the cases the overall distribution is marginally inflated (λGC < 1.16).