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Leucine zipper motifs in the FIAT protein sequence. The 524-amino acids FIAT protein contains three identifiable leucine zipper domains (boxed in black) with the leucines in each zipper highlighted. Amino acids 194-222 were deleted to create the FIAT ZIP2 DEL mutant. The leucine-to-alanine substitutions engineered to generate mutants M1 (L142A/L149A), M2 (L208A/L215A/L222A), and M3 (L441A/L448A) are indicated above the boxed leucine zipper domains.
