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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Ann Hum Genet. 2008 Jul 24;72(Pt 6):801–811. doi: 10.1111/j.1469-1809.2008.00465.x

Figure 2.

Figure 2

Correlation between prevalence and risk allele frequency contributes to statistical power. The correlation is shown on the x-axis as Pearson’s coefficient, and statistical power is shown on the y-axis without adjustment for type I error. Suppose five subpopulations are of the same size in a local area and the RR of a risk allele is 1.2 in the local population. The Figure 2a shows results for a risk allele with frequency of 0.1 in the local population; the Figure 2b shows results for a risk allele with frequency of 0.5 in local population; the Figure 2c shows results for a risk allele with frequency of 0.9 in the local population.