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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Mol Microbiol. 2008 Apr 28;69(1):15–29. doi: 10.1111/j.1365-2958.2008.06264.x

Fig. 4. Strong anti-OspA responses are induced by OspC-deficient B. burgdorferi with OspA expression under control of the ospC regulatory elements.

Fig. 4

Groups of 10 mice were infected with either ΔospC/FL or ΔospC/CpospA spirochetes for 4 mo. Serum samples were collected and analyzed for anti-OspA antibody titers by an end-point ELISA. No response was detected in four of the mice infected with the genotype ΔospC/FL so that only six datum points are shown for this group. The average titers (horizontal lines) for each group are also presented.