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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Mol Microbiol. 2008 Apr 28;69(1):15–29. doi: 10.1111/j.1365-2958.2008.06264.x

Table 6.

OspC-deficient B. burgdorferi with increased OspA expression can persist in the skin but not heart or joint tissue of chronically infected immunocompetent mice.a

Clone No. of cultures positive/Total no. of specimens examined
Heart Joint Skin All sites
ΔospC/FL/1 5/5 5/5 5/5 15/15
ΔospC/FL/2 5/5 4/5 5/5 14/15
ΔospC/CpospA/1 0/5 1/5 5/5 6/15
ΔospC/CpospA/2 1/5 1/5 5/5 7/15
a

Groups of five BALB/c mice were inoculated with 104 spirochetes of the clone ΔospC/FL/1, ΔospC/FL/2, ΔospC/CpospA/1, or ΔospC/CpospA/2. Mice were sacrificed 4 mo post-inoculation; heart, tibiotarsal joint and skin specimens were harvested for spirochete culture in BSK-H complete medium.