. Author manuscript; available in PMC: 2009 Aug 1.

Published in final edited form as: Epilepsy Behav. 2008 Jun 2;13(2):290–294. doi: 10.1016/j.yebeh.2008.04.012

TABLE 1.

Summary of the Cosinor analysis of the daily rhythms of seizure behavior in adult Aldh5a1^−/−and WT mice

Variable	Group	N	Light phase	Dark phase	Mesor	Amplitude	Phase	Period (h)	R²
MV	WT	8	9.08 ± 2.14	11.17 ± 3.19	10.13 ± 2.65	5.67 ± 2.01	−5.08 (1855)	24.55 ± 0.78	0.43
	−/−	6	24.42 ± 2.55^b	30.86 ± 2.06^*,^b	27.23 ± 1.17^b	10.42 ± 1.65^b	−4.16 (1950)	25.26 ± 0.28	0.76^b
JFP	WT		0.25 ± 0.02	0.57 ± 0.12^*	0.44 ± 0.071	0.17 ± 0.07	−2.16 (2150)	24.88 ± 0.33	0.16
	−/−		2.07 ± 1.06^a	3.89 ± 1.47^b	2.99 ± 0.22^b	2.04 ± 0.31^b	−4.28 (1943)	24.74 ± 0.19	0.72^b
Seizures	−/−		0.25 ± 0.05	0.42 ± 0.03	0.32 ± 0.06	0.24 ± 0.08	−3.86 (2008)	25.53 ± 1.02	0.73

Note. Data are expressed as means ± SEM. Phase data are expressed as hours before (−) subjective midnight with the clock time in parentheses. MV, movement velocity; JFP, jumps above the floor plane; WT, wild type. R² = coefficient of determination.

P < 0.05.

P < 0.01 for between-group comparisons of rhythm parameters (ANOVA).

P < 0.05 for within-group comparisons of dark/light phase MV and JFP (two-tailed, paired sample t test).