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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Mol Pharmacol. 2008 Aug 22;74(5):1333–1344. doi: 10.1124/mol.108.048355

Fig. 5. Incorporation of SUR2A into T1 results in longer burst durations.

Fig. 5

A, representative single-channel recordings for T1 and T1+SUR2A. The dotted lines correspond to the zero current levels. Channel openings are in the downward direction. The mean burst duration for T1 was increased ~2-fold in the presence of SUR2A (Table 2). B, the single-channel closed times and open dwell times were fitted by maximum likelihood with sums of exponential functions. For both channels, the closed and open times were best fitted with four and one exponentials, respectively. The values of the fit parameters (see Methods for the definition of the symbols) are shown in the panels.