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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: J Neurosci Res. 2008 Nov 1;86(14):3240–3245. doi: 10.1002/jnr.21762

Figure 1.

Figure 1

(A) Brain water content was assayed at 24 h after ICH by using wet/dry method. Brain edema was significantly reduced in CD18-knockout mice compared with wild type mice (*p<0.05, ANOVA). (B) The Garcia neuroscoring system was used for neurological deficit evaluation. CD18 null mice showed a noticeable but insignificant amelioration of neurological function (C) Mortality was calculated by dividing the number of dead animals by the number of total animals used in each group at 24 hrs after ICH (Ostrowski et al., 2006). Mortality rate was significantly reduced in the CD18-knockout mice (*p<0.05, Chi square test). (D) In MPO activity assay we used whole hemispheres ipsilateral to hemorrhage. CD18 deficiency was associated with a reduced MPO activity, by 70%, although statistical significance was not reached (p>0.05, t-test).