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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Mol Pharmacol. 2008 May 5;74(2):392–402. doi: 10.1124/mol.108.046946

Figure 3.

Figure 3

Analysis of TNF-α production induced by Compounds 1 and 2 in murine peritoneal macrophages, human monocytic cells THP-1, human MonoMac6 macrophages, and human monocyte-derived macrophages. The indicated cells were incubated with buffer (0) or the indicated concentrations of Compound 1 (○), 2 (●), or LPS (50 ng/ml) (◆) for 24 hr, and TNF-α was measured in the cell supernatants by ELISA. The data are presented as the mean±SD of triplicate samples from one experiment, which is representative of three independent experiments.