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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: J Pharmacol Exp Ther. 2008 Aug 5;327(2):425–431. doi: 10.1124/jpet.108.141283

Figure 6. Effect of 8-bromo-cGMP on the IP3 receptor in the uterine artery.

Figure 6

Uterine arteries were treated with 100 μM 8-bromo-cGMP for 30 min. Saturation binding of [3H]IP3 to membranes prepared from the uterine arteries was conducted as described in Methods. Panel A shows the specific binding curves for [3H]IP3. Data points represent means of triplicate determinations in a single experiment. Panel B shows IP3 binding dissociation constant (KD) and IP3 receptor density (Bmax) determined in the saturation binding. Data are means ± SEM of the tissues from five animals. * P < 0.05