Table 1.

Permeabilities (P) and Efflux Ratios of Prenylated Flavonoids^⋆

Compound(10μM)	PAB(cm/s)		PBA(cm/s)		Efflux Ratio
	Mean·10−6	SD·10−7	Mean·10−6	SD·10−7	PBA/PAB
Epimedin A	0.322	0.39	1.59**	1.94	4.94
Epimedin B	0.276	0.20	1.33*	1.90	4.82
Epimedin C	0.423	0.025	1.20**	1.05	2.85
Icariin	0.591	0.091	2.36***	0.71	3.99
Baohuoside I	1.460	2.02	14.30***	1.25	9.84

^⋆Experiments were performed in triplicate at 37°C, pH 7.4 HBSS. Donor and receiver volumes were 2.5 ml. The sample taken time was 0, 1, 2, 3, 4 hr after incubation. Absorptive permeability was expressed as P_AB, whereas secretory permeability was expressed as P_BA. Data are expressed as mean ± SD (N=3). One-way ANOVA with Tamhane’s post hoc was used to analyze the data statistically. The statistically significant difference (as shown by the “*” symbol) is between the secretory permeabilities and absorptive permeabilities of the prenylated flavonoids. The level of significance is signified by

^***p<0.001,

^**p<0.01, and

^*p<0.05.