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HPLC analyses of cultures of S. argillaceus recombinant strains harboring different “sugar plasmids”. ✩ Premithramycin-like compounds. ★ Mithramycin-like compounds. Peaks corresponding to the different compounds are indicated as follows: M: mithramycin; A: premithramycin A1; P: premithramycinone; peaks a–i: mithramycin derivatives purified from the recombinant strains.
