Figure. 5.
Efficacy of photodynamic therapy for polymer conjugates in MDA-MB-231 xenografts bearing nude mice. Efficacy is expressed as the percentage increase in relative tumor size for the mice receiving PEG-PGA-(Gd-DO3A)-Mce6 (◆), PGA-(Gd-DO3A)-Mce6 (■) at a Mce6 equivalent dose of 6.0 mg/kg, and PGA-(Gd-DO3A), at a dose of 0.045 mmol-Gd/kg (▲) after the tumors were irradiated at 18 and 24 hours post-injection.