Table 3.
Comparison of Gibb’s Free Energy Change (ΔΔG) for Transfer of Each Methylene Group of a Series of n-Alcohols From Water to the Site of Action for the Present Study With Published Results. Values for the Present Study Were Calculated From Figure 8B
| ΔΔG
|
Reference | ||
|---|---|---|---|
| cal/mol/CH2 | kJ/mol/CH2 | ||
| Tadpole | −800 | −3.35 | Alifimoff et al. (1989) |
| Nav1.2 | −835 | −3.49 | Present study |
| Squid axon | −726 | −3.04 | Haydon and Urban (1983) |
| NMDA receptor | −478 | −2.00 | Peoples and Weight (1995) |