Figure 2. Differential expression of MDR-1 and MRPs genes in primary human endothelial cells.
Total RNAs from HAECs, HPAECs, HDMVECs, HBMVECs and HUVECs were analyzed for MDR-1, MRP-1, MRP-2, MRP-3, MRP-4 and MRP-5, gene expression by RT-PCR. In (A), the representative gel pictures show the amplified products obtained in each of the EC types examined (lanes 1–5) along with a molecular weight marker (lane-M). In (B), the bar graphs show the normalized densitometric ratios of the PCR products (n=5). The error bars represent ±SEM of values.