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. Author manuscript; available in PMC: 2008 Oct 29.
Published in final edited form as: Exp Biol Med (Maywood). 2008 Jun 5;233(9):1149–1160. doi: 10.3181/0802-RM-59

Figure 5. MDR-1 and MRP-mediated efflux of Zidovudine from HBMVECs and HAECs.

Figure 5

Intracellular accumulation and temporal efflux of 3H-zidovudine was measured in both HBMVECs (A) and HPAECs (B), similar to the saquinavir efflux studies. The percent changes in normalized values (CPM/ µg of protein) are depicted in the line graphs (n=3). Error bars represent ±SEM and significant differences in zidovudine accumulation and temporal efflux are indicated by P values (* p< 0.05; ** p< 0.01).