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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Drug Metab Dispos. 2008 May 7;36(8):1722–1728. doi: 10.1124/dmd.108.021881

Fig. 5.

Fig. 5

Dox-induced cardiac apoptosis. Three-month-old, male mice were given a single i.p. injection of Dox (at 20 mg/kg; n = 5) or saline (n = 4). Two days after treatment, apoptotic cells were detected by TUNEL assay in paraffin-embedded heart sections as described in Materials and Methods. **, P < 0.01, compared to saline-treated mice of the same strain (Student’s t-test).