TABLE 1.
Western Blot-determined Relative Content of Bcl-2 and Caspase-3 and Tissue Culture-determined EC50 (NCS) for Seven Tumor Cell Lines
| Cell Line | Relative Bcl-2 Content Average (Experiment 1, Experiment 2) | Relative Caspase-3 Content Average (Experiment 1, Experiment 2) | EC50 (NCS) (nM) (n = 3) |
|---|---|---|---|
| SK-N-SH | 82 (33, 132) | 69 (69, 69) | 19 ± 1 |
| U87 | 53 (7, 99) | 60 (47, 74) | 29 ± 6 |
| IMR-32 | 126 (99, 152) | 75 (67, 82) | 14 ± 1 |
| SK-N-MC | 106 (66, 147) | 75 (83, 67) | 11 ± 1 |
| DAOY | 71 (38, 105) | 34 (1, 66) | 53 ± 26 |
| MCF-7 | 80 (66, 93) | 0.1 (0.2, 0) | 97 ± 28 |
| BT474 | 62 (64, 60) | 28 (9, 46) | 83 ± 3 |