Table 2.
Cox proportional hazards model for breast cancer end point in WHEL Study women on tamoxifen at baseline (n = 864)
| Predictor | Hazard ratio | 95% CI |
|---|---|---|
| Stage of breast cancer* | ||
| I (reference) | 1.00 | - |
| II | 1.61 | (0.92−2.83) |
| III | 4.26 | (2.36−7.68) |
| Grade of cancer | ||
| I (reference) | 1.00 | |
| II | 2.02 | (0.98−4.14) |
| III | 1.97 | (0.91−4.26) |
| Missing grade | 0.72 | (0.22−2.38) |
| Hot Flashes at baseline | ||
| No (reference) | 1.00 | - |
| Yes | 0.50 | (0.36−0.69) |
*
Tumor stage was originally reported using AJCC 4th staging criteria, and then recalculated using AJCC 6th staging
Model is also adjusted for age, time interval between diagnosis and study entry, tumor hormone receptor status, and baseline dietary fiber intake