Table 4.
Final General Linear Models
| Subjective Social Support | Social Interaction | |||
|---|---|---|---|---|
| F value | p value | F value | p value | |
| Genotype | 5.33 | 0.0216 | 3.66 | 0.0567 |
| Depression | 81.62 | < 0.0001 | 28.96 | < 0.0001 |
| Education | 0.15 | 0.6967 | 3.16 | 0.0762 |
Social support measures were log-transformed. Genotype (Val66 homozygote or Met66 allele carrier) and depression (MDD or nondepressed) were dichotomous variables. Age and sex were not included in models as they were not significantly different between BDNF genotype groups, and not significantly related to social support measures. Education (in years) was a continuous variable. Each variable had 1 degree of freedom while the overall model had 357 degrees of freedom. Initial models included a depression by genotype interaction term, however these were not statistically significant so were removed.