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Minimal effects of a ryanodine receptor blocker TMB-8 on presynaptic Ca2+ transients evoked by single shocks. (A) Effects of TMB-8 (10 μM) on presynaptic Ca2+ transients evoked by single shocks to mossy fibers. Graphs represent the time course of amplitudes of Ca2+ transients (ΔF) and F. (B) Effects of TMB-8 on the field EPSPs recorded simultaneously.
