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. 2008 Nov 4;3(11):e3644. doi: 10.1371/journal.pone.0003644

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Teichmann et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A, single mdx fiber with global Ca²⁺ waves rather than increased ECRE activity following osmotic challenge (hypertonic solution, 2 mM Ca²⁺). Numbers indicate the frame number during a 50 frame XYT series. Scale bar: 20 µm. White line: ROI from which spatial profiles (B) were obtained. Ca²⁺ waves were never observed in wt or MinD fibers.