Skip to main content
. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Biochem Pharmacol. 2008 Jul 2;76(5):589–596. doi: 10.1016/j.bcp.2008.06.012

Figure 2.

Figure 2

Measurement of the rate constant of superoxide reaction with honokiol by competition with spin probe CMH (1mM) in cytochrome P-450 reductase system (10 µM menadione, 0.1mM NADPH, 1µU cytochrome P-450 reductase). (A) Accumulation of CM-nitroxide in superoxide generating system in the presence of various concentrations of honokiol. CM accumulation was followed by an increase in intensity of low field component of ESR spectrum indicated by arrow (insert). (B) Inhibition of CM accumulation by honokiol. ESR settings were as described in Materials and Methods.